You will receive a 500 - Internal Server Error. This is HTTP Error 500.24: An ASP.NET setting has been detected that does not apply in Integrated managed pipeline mode.
It occurs because ASP.NET Integrated mode is unable to impersonate the request identity in the BeginRequest and AuthenticateRequest pipeline stages.
1) If your application does not rely on impersonating the requesting user in the BeginRequest and AuthenticateRequest stages (the only stages where impersonation is not possible in Integrated mode), ignore this error by adding the following to your application’s web.config:
<validation validateIntegratedModeConfiguration="false" />